Clomid Super Ovulation – A First Line of Defense Against Infertility

Ovulation disorders are one of the most common causes of female infertility. The fertility drug Clomiphene Citrate (under the brand names Clomid and Serophene) optimize the body’s ability to produce and release an egg during ovulation, and may be the only therapy needed to produce a pregnancy.

Dr. Mark Rispler with Innovative Fertility Center incorporates clomiphene into his treatment regimens for several reasons:

  • Clomiphene has been in use for over 30 years and has proven to be safe.
  • Clomiphene consistently produces results. Approximately 80% of women taking Clomid will ovulate.
  • Few side effects are associated with Clomid or Serophene.

Known as super ovulation, a cycle with the fertility drug Clomid or Serophene is often the first prescribed therapy for women diagnosed with ovulation disorders, polycystic ovarian syndrome, unexplained infertility or a luteal phase defect. Dr. Rispler may also prescribe Clomid or Serophene during a male infertility treatment cycle.

Inducing Ovulation Begins with Day 1

Day 1 in a menstrual cycle is the first day of a full flow. Clomiphene is taken as a pill beginning with the 3rd or 5th day of a monthly cycle, continuing to day 7 or 9 to cause the pituitary gland to secrete higher levels of the hormone FSH. A domino effect of follicular growth, followed by increased estrogen in the bloodstream and resulting LH surge will signal the ovaries to ovulate.

Dr. Rispler will perform a mid-cycle sonogram to determine the effectiveness of the dosage: How many follicles are forming? Does the uterine lining look sound? Is cervical mucus present?

At this point in fertility treatment, Dr. Rispler may recommend an injection of HcG to induce ovulation, or supplemental gonadotropin injections. You will discuss the two options for fertilization: timed intercourse, or intrauterine insemination (IUI).

Clomid and Timed Intercourse

Dr. Rispler will advise you on the specific days to have intercourse while on a Clomid regimen. While this is a minimally invasive approach to fertility treatment, we require a mid-cycle visit as well as a pelvic exam late cycle to check the ovaries for cysts.

Clomid or Serophene and IUI

Your fertility treatment cycle leading to IUI, or artificial insemination, will involve the same process as Clomid and timed Intercourse. With IUI, your partner will produce a semen sample for the IVF lab at Innovative Fertility Center. Only healthy, strong and toxin-free sperm are transferred into the uterus via a thin catheter during the in-office insemination.

Dr. Rispler advises moving on to other fertility treatment options after 6 ovulatory cycles of Clomid.

The most common side effects associated with Clomid.

  • Moodiness
  • Changes in cervical mucus
  • Headache
  • Blurred vision
  • Ovarian cysts
  • Multiples

Dr. Rispler has advanced training as a reproductive endocrinologist and more than 20 years of experience managing controlled ovarian stimulation to induce ovulation. If you have determined that you do not ovulate or ovulate irregularly, consider contacting Innovative Fertility Center for an appointment to discuss super ovulation.